Myosynergy Elite Presale

PRESALE - ETA 1/20/25

Presale will be limited to the first 200 bottles in order to meet production costs. Retail price will be $69.99.

Presale price - $56.99 (discount code can be used).

MYOSYNERGY ELITE 2025

MyoSynergy Elite is a comprehensive blend of ingredients that all work together to enhance anabolic pathways via multiple directions as well as inhibiting catabolic, destructive angles. MyoSynergy Elite will enable you to enhance your training to maximize and even go beyond your genetic limitations on muscle mass.

MyoSynergy - Become a Breed Beyond

Let's do a quick overview of what angles we will be covering with MyoSynergy.
IGF1--->AKT--->mTORc1 (arrow means a subsequent pathway is activated) - IGF-1 is an anabolic hormone released in response to workouts (notably mechanical stress). When it attaches to its receptor (IGF-1r) it triggers AKT (aka Protein Kinase B) which, in turn, activates mTORc1. Ultimately mTORc1 is the signal that causes a rapid increase in muscle protein synthesis and hypertrophy.

At the same time IGF-1--->AKT---|GSK3b (vertical line means that the pathway is blocked) causes inhibition of Glycogen Synthase Kinase 3b which prevents atrophic pathway from activating, thus preventing muscle breakdown.

Myostatin/TGFb1/SMAD2/3
Myostatin is the bad guy here. Myo meaning Muscle, statin meaning to stop or cause to be inactive, myostatin is a protein that prevents muscular adaptation to exercise (e.g. muscle growth). Myostatin activates members of the TGFb1 family, and eventually triggers activation of SMAD2/3 which then not only prevents muscle growth, but triggers muscle breakdown (atrophy).

BMP/SMAD1/5/8 Bone Morphogenetic Proteins are incredibly potent signal proteins that cause stem/satellite cell differentiation. By drawing on this pool of undifferentiated cells, they can be pushed to form new bone, connective, and muscle tissue resulting in rapid hypertrophy.

SMAD4 is an escort molecule. Both SMAD2/3 (atrophic) and SMAD 1/5/8 (hypertrophic) compete to join with SMAD4 to move to the nucleus and exert their effects. Inhibition of SMAD2/3 means that SMAD1/5/8 has unrestricted access to SMAD4 and the hypertrophic effects are greatly amplified.

Myosynergy stands as a new generation of products that will prevent muscle atrophy and amplify hypertrophy.

INGREDIENTS:

Astragalus Membranaceus (50:1) - With a whopping 50:1 potency, AM enhances BMP2, IGF-1, and Human Growth Hormone signals, while inhibiting the final step in Myostatin atrophy signals

Angelica Sinensis (50:1) - Enhances Decorin release to trap Myostatin, enhances IGF-1 signals, and amplifies stem cell recruitment to form new muscle cells

Apigenin-Proline Crystalline Complex - Enhances anabolic BMP signals and amplifies stem cell recruitment, while blocking atrophy signals

Puerarin-Ascorbic Acid Crystalline Complex - Weak estrogenic effect to blunt stronger estrogen signals, enhances IGF-1 signals, inhibits atrophy, inhibits aromatase, blocks final Myostatin downstream effects and enhances anabolic BMP effects

Quercetin-Nicotinamide Crystalline Complex - Potent Myostatin inhibitor, enhances neuromuscular junction for maximum strength and CNS recovery, enhances BMP anabolic signal, inhibits GSK3b, and amplifies IGF-1 signals

Lithocholic Acid - Extremely potent TGR5 agonist, increases protein synthesis and stem/satellite cell differentiation for new muscle cells, amplifies IGF-1 signals

Fructus Schizandra (50:1) - Potent Myostatin inhibitor, blunts atrophy signals, amplifies IGF-1 signals, activates mTORc1

Broccoli Sprout Extract - Containing Sulphoraphane, which inhibits expression of Myostatin protein at the epigenetic level

Brown Mustard/Myrosinase - Enhances sulphoraphane synthesis and absorption

-(-)Epicatechin - Potent Myostatin inhibitor/blocker via increase in Follistatin production, PXR activator

Genistein-Nicotinamide Complex - ERb activator, amplifies IGF-1 signals, increases stem cell recruitment to form new muscle

Shilajit - Potent absorption enhancer, potential androgen signal amplifier, Myostatin blocking via Decorin release 

Indole-3-Propionic Acid - Extremely potent Myostatin inhibitor, increases new muscle cell differentiation

Black Pepper Extract - Absorption enhancer

L-Borneol - Extremely potent absorption enhancer

Full writeup available here:

https://anabolicminds.com/community/threads/evomuse-presents-myosynergy-elite-2025-version.338751/

Serving Size - 3 Capsules
Servings Per Bottle - 60

Directions: Take 3 capsules with morning meal, then another 3 capsules 8 hours later with a small amount of food. MyoSynergy does not directly affect masculine sex hormones, so it is perfectly fine for women. As of this writing, to the extent of our knowledge, none of the ingredients are banned for tested competitions. However, be sure to check with any testing/ruling bodies prior to use. 

Do NOT exceed recommended dosage. Avoid nicotine. Be sure to take the RDA of Zinc and Magnesium every day. Minimum protein intake of 0.8-1 gram per pound of lean body mass is recommended. A cycling protocol of 2 months on, 2 weeks off is essential.